超级大胖子金斯教授（艾迪墨菲 Eddie Murphy 饰演）虽然学术高明，心地善良，但因为体型问题一直成为大家的笑柄。直到有一天，金斯教授发现自己研制的新药成功了，这种药水能改变小白鼠的DNA，使其体重减轻，似乎金斯教授就要迎来自己的新生活了。金斯教授一直钟情于化学教员的卡洛小姐（贾达萍克史密斯 Jada Pinkett Smith 饰），一次…
Peggy, a former addict, who decides to make a new start after the death of her beloved mother with whom she lived in the small desert town of Yucca Valley, California, makes a life-changing decision to become a private investigator.
